Friday, November 26, 2010

Reduce High Blood Pressure - New Operation

By Jamesina Goulbourne


There is a new surgical operation called Renal Sympathetic-Nerve Ablation, renamed Renal De-nervation, which is carried out roughly within 60 minutes. It is a new approach to lowering high blood pressure that was developed by the US company Ardian who sponsored the trials. During the procedure, radio frequency (RF) ablation is used by the aid of a catheter to sear renal sympathetic nerves, with the avoidance of other areas such as the abdomen or pelvis being affected.

The catheter is first inserted at the Femoral artery then through to the Distal (Distant) Renal Artery near the kidneys. It is withdrawn in stages and rotated throughout the artery to sear the nerves responsible for sending signals from the brain to the kidneys. These signals are sent to stimulate the kidneys into raising blood pressure.

Fred Quatromini, a patient involved in an International trial of this new surgical procedure was operated on in December 2009 in Bethnal Green at the London Chest Hospital. After he was examined after a year and was found to be fit and doing well with his blood pressure reduced. Another patient Anthony Henry, a retired chef aged 68, was also one of the first to be operated on in Briton as part of the same trial. His blood pressure had a significant drop after 14 days which showed promise, and a good result was expected of the rest of the trial patients after a period of at least 12 weeks.

The International clinical trials for this new innovative surgery started with 45 out of 50 patients from 5 Australian and European centres, who received treatment between June 2007 and November 2008. Having been completed, the results of that year long trial were published in the Lancet on March 30, 2009. In brief, they were successful. Only 17% of those who took part did not experience a reduction in blood pressure, whereas 83% dropped their blood pressure by 10 mmHg diastolic or greater, up to 25 mmHg.

The results certainly bring hope. But before we think this is a cure, researchers need to allow more time to observe how the patients get along. Not only that, the nerves can heal again after a while. What would be done then? Will other health problems arise due to the nerves being seared? These are just a sample of the questions being asked.

Keep in mind too, that presently this new operation is being offered only to those who have tried drugs to bring down their blood pressure but to no avail, which is classed as resistant hypertension. It is too early to raise your expectations.

But then again, maybe your hope will soon be realised, because Dr Krum of the Monash University, Australia believes there is potential for other patients who have non-essential hypertension and other miner forms of the disease. Time will tell, but in the meantime good eating habits and a daily exercise routine are known to help reduce hypertension. Who knows? Perhaps you will not need the new surgery after all.




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